臭氧大自血聯(lián)合CT 引導(dǎo)下連續(xù)腰交感神經(jīng)阻滯治療下肢血栓閉塞性脈管炎

劉智慧  孫永海  趙國利  路桂軍  楊靜

【摘要】目的 探討臭氧大自血聯(lián)合CT 引導(dǎo)下連續(xù)腰交感神經(jīng)阻滯治療血栓閉塞性脈管炎(thromboagiitis oblit- erans,TAO) 的臨床療效、安全性及作用優(yōu)勢。方 法 選取2012年5月至2015年9月解放軍總醫(yī)院收治的有疼痛癥狀 的 TAO 患者作為研究對象。采用隨機(jī)數(shù)字表法分為對照組和試驗(yàn)組。對照組給予單純CT 引導(dǎo)下連續(xù)腰交感神經(jīng) 阻滯治療，試驗(yàn)組給予臭氧大自血聯(lián)合CT引導(dǎo)下連續(xù)腰交感神經(jīng)阻滯治療。比較2組患者視覺模擬評分(VAS)、疼 痛緩解時(shí)間及肢體缺血程度分期變化等指標(biāo)。 結(jié) 果 38例患者納入本研究，每組19例。2組患者一般情況比較，差 異無統(tǒng)計(jì)學(xué)意義。各組治療后不同時(shí)點(diǎn)與治療前的VAS 評分比較，差異均有統(tǒng)計(jì)學(xué)意義(P<0.05);2 p="">0.05),     治療第10、30天試驗(yàn)組VAS評分較對照組明顯降低，差異有統(tǒng)計(jì)學(xué) 意義(P<0.05) 。 結(jié) 論 臭氧大自血聯(lián)合CT引導(dǎo)下連續(xù)腰交感神經(jīng)阻滯治療可以改善末梢血運(yùn)循環(huán)、增加體內(nèi)氧 供，緩解TAO患者的疼痛。
【關(guān)鍵詞】 血栓閉塞性脈管炎；臭氧；腰交感神經(jīng)阻滯

      Ozone autohemotherapy combined with continuous lumbar sympathetic block guided with CT in treatment of patients with lower extremity thrombosis obliterans Liu Zhihui,Sun Yonghai,Zhao  Guoli,Lu  Guijun,Yang  Jing.
Anesthesia and Operation Center,Chinese PLA General Hospital,Bejing 100853,China Corresponding   author:Sun   Yonghai,Email:sunyonghai68@aliyun.com

      【Abstract]Objective     To  evaluate  the  safety,effectiveness  and  the  advantages  of  ozone  autohemotherapy  com- bined with continuous lumbar sympathetic block guided with CT in treatment of patients with lower extremity thrombosis obliterans.  Methods The thrombosis obliterans patients who were admitted to the hospital from May 2012 to September 2015 for pain were recruited and randomly divided into the control group and the treatment group.The control group were treated by simple CT-guided continuous lumbar sympathetic block therapy,while the treatment group were applied ozone autohemotherapy combined with CT-guided continuous lumbar sympathetic block therapy.All the patients were analyzed in terms of the VAS scores,pain remission time,changes in the degree of limb ischemia  stage and other aspects. Results A total of 38 patients were identified.The demographic data were similar in two groups.There was significant difference in  theVAS  scores  between  before  and  after  treatment  in  two  groups(P<0.05).therewas no="" p="">0.05)of  the VAS on the third day between two groups.There were significant differences of the pain scores,the de

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